One activity of the CFG's Glycan Array Synthesis Core (Core D) was to produce glycosyltransferases for use in chemo-enzymatic synthesis of glycans. Several useful glycosyltransferases were produced with the intention of distributing them to investigators through the Reagent Bank. However, distribution of these enzymes was restricted by the institutions that originally provided them. TSRI worked with each institution to remove these restrictions. Permission was obtained to distribute the enzymes listed below, which may be requested using the standard CFG resource request form. To cover the cost of distributing materials, investigators will be requested to pay a $250.00 handling fee plus shipping costs for each resource request. A request can include more than one reagent.
Glycosyltransferases used by Core D to synthesize the glycan library.
The table below lists the enzymes used by Core D for synthesis of glycans for the glycan array library. Blue highlighting on 'Entry' numbers signifies enzymes that have been produced by Core D for the reagent bank; you may request these enzymes through the normal request process, and approved requests will be filled when distribution rights have been obtained. Further expansion of the reagent bank has been suspended due to lack of resources. If you wish to request the expression systems or cDNAs of any of the enzymes for use in your own laboratory, please contact the contributor directly to obtain permission. To cover the cost of distributing materials, investigators will be requested to pay a $250.00 handling fee plus shipping costs for each resource request. A request can include more than one reagent.