Glycolipid: a-Galactosyl ceramide (aGalCer)

Buffer: DMSO

Purity: See NMR

Storage temperature: -20ºC

Activity: Active in CD1-mediated IL-2 stimulation in NKT1.2 cells as assayed by ELISA in M. Kronenberg’s laboratory.

References:

Morita M, Motoki K, Akimoto K, et al. Structure-activity relationship of alpha-galactosylceramides against B16-bearing mice. J Med Chem. 1995;38:2176-2187.

Matsuda JL, Naidenko OV, Gapin L, et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med. 2000;192:F15-20.