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Functional Glycomics Update

Welcome to the August Functional Glycomics Update, your one-stop resource for news, highlights and research on glycobiology.

Featured articles

Specially written Editor's reviews of the hottest new articles

E-selectin ligand formation: Cancer cells dress up for metastasis

Fucosylation is central to the formation of E-selectin ligands in neutrophils and metastasizing cancer cells, however, both cell types initiate endothelial adhesion by forming different ligands.

Glycobiology 22 July 2008 (doi:10.1093/glycob/cwn070)

Lectin-glycan interactions: A meeting's harvest

The 23rd Interlec meeting presented a wealth of data that added new evidence to how lectin-glycan interactions orchestrate cellular fate and influence health and disease conditions.

23rd International Lectin Meeting, 11th – 16th July 2008.

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Research Highlights

Synopses of important recent articles

Channel function: Klotho increases life span by cutting the glycan thread

The transmembrane protein Klotho aids the ion maintenance function of the TRPV5 channel by cleaving sialic acids from the TRPV5 N-glycan, thereby exposing lactosamines that anchor the channel in the cell membrane.

Functional Glycomics Gateway (14 August 2008)

Plant lectins: Sugar sensing for pollen development

A lectin receptor-like kinase encoded by the gene At3g53810 is required for pollen development in Arabidopsis thaliana.

Functional Glycomics Gateway (14 August 2008)

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